Team Members:

Dr. Smita Pakhale
Kathy Vandemheen, RN, MScN
Dr. Andrea Gershon
Dr. Mohsen Sadatsafavi 
Dr. Tetyana Kendzerska

Goals

• To determine the burden of undiagnosed airway disease (asthma and COPD) in at-risk Canadian adults.
• To determine whether early treatment of newly diagnosed airflow obstruction affects patient quality of life and health outcomes.

Publications

Aaron SD, Tan WC, Bourbeau J, Sin DD, Loves RH, MacNeil J, Whitmore GA;Canadian Respiratory Research Network. Diagnostic Instability and Reversals of COPD Diagnosis in Subjects with Mild to Moderate Airflow Obstruction. Am J Respir Crit Care Med. 196(3): 306-314, 2017.

Aaron SD, Vandemheen K, FitzGerald JM, et al.  Reevaluation of Diagnosis in Adults with Physician-Diagnosed Asthma. JAMA, (2017); 317(3): 269-279.

Gershon A, Mecredy G, Croxford R, To T, Stanbrooke M, Aaron SD.  Association of pulmonary function testing and health outcomes in individuals with physician-diagnosed COPD.  A population study.  CMAJ, in press DOI:10.1503/cmaj.151420, 2016.

Ten-year trends in direct costs of asthma: a population-based study.
Tavakoli H, FitzGerald JM, Chen W, Lynd L, Kendzerska T, Aaron S, Gershon A, Marra C, Sadatsafavi M.  Ten-year trends in direct costs of asthma: a population-based study.  Allergy, doi: 10.1111/all.12993, 2016

The Impact of a History of Asthma on Long-Term Outcomes of People with Newly Diagnosed Chronic Obstructive Pulmonary Disease: A Population Study. 
Kendzerska T, To T, Aaron SD, et al. The Impact of a History of Asthma on Long-Term Outcomes of People with Newly Diagnosed Chronic Obstructive Pulmonary Disease: A Population Study.  J Allergy Clin Immunol, 2016 Aug 28. pii: S0091-6749(16)30706-0. doi: 10.1016/j.jaci.2016.06.026.

Gershon A, Hwee J, Chapman K, Aaron SD, O’Donnell D, et al.  Factors Associated with Undiagnosed and Overdiagnosed COPD.  European Resp J 48(2):561-4, 2016.

Influence of Country-Level Differences on COPD Prevalence.
Aaron SD, Gershon A, Gao C, Yang J, Whitmore GA.  Influence of Country-Level Differences on COPD Prevalence.  Int J COPD, 11: 2305-2313, 2016.