Publications
Articles de revue
Undiagnosed COPD Contributes to the Burden of Health Care Utilization: Data from the CanCOLD Study.
Labonté LE, Tan WC, Li PZ, Mancino P, Aaron SD, Benedetti A, Chapman KR, Cowie R, FitzGerald JM, Hernandez P, Maltais F, Marciniuk DD, O'Donnell D, Sin D, Bourbeau J; Canadian Respiratory Research Network and the CanCOLD Collaborative Research group. Undiagnosed COPD Contributes to the Burden of Health Care Utilization: Data from the CanCOLD Study. Am J Respir Crit Care Med. 2016 Feb 2.[Epub ahead of print]
Biosignature for airway inflammation in a house dust mite-challenged murine model of allergic asthma.
Piyadasa H, Altieri A, Basu S, Schwartz J, Halayko AJ, Mookherjee N. Biosignature for airway inflammation in a house dust mite-challenged murine model of allergic asthma. Biol Open. 2016 Jan 6;5(2):112-21. doi: 10.1242/bio.014464.
Pulmonary gas exchange abnormalities in mild COPD: implications for exercise intolerance
Elbehairy AF, Ciavaglia CE, Webb KA, Guenette JA, Jensen D, Mourad SM, Neder JA, O’Donnell DE; on behalf of the Canadian Respiratory Research Network. Pulmonary gas exchange abnormalities in mild COPD: implications for exercise intolerance. Am J Respir Crit Care Med published online March 31, 2015 as doi: 10.1164/rccm.201501-0157OC.
Effect of age-related ventilatory inefficiency on respiratory sensation during exercise
Faisal A, Webb KA, Guenette JA, Jensen D, Neder JA, O’Donnell DE; on behalf of the Canadian Respiratory Research Network. Effect of age-related ventilatory inefficiency on respiratory sensation during exercise. Respir Physiol Neurobiol 2015; 205: 129-139. [doi:10.1016/j.resp.2014.10.017]
Physiological characterization of the chronic bronchitis phenotype in GOLD grade 1B COPD
Elbehairy A, Raghavan N, Cheng S, Yang L, Webb KA, Neder JA, Guenette JA, Mahmoud MI, O’Donnell DE; on behalf of the Canadian Respiratory Research Network. Physiological characterization of the chronic bronchitis phenotype in GOLD grade 1B COPD. Chest published online November 13, 2014 as doi: 10.1378/chest.14-1491.
Disruption of pulmonary lipid homeostasis drives cigarette smoke-induced lung inflammation in mice
Morissette MC, Shen P, Thayaparan D, Stämpfli MR. Disruption of pulmonary lipid homeostasis drives cigarette smoke-induced lung inflammation in mice. Eur Respir J. 46(5):1451-1460 2015.
Should COPD stand for “Comorbidities-related Obstructive Pulmonary Disease”?
Sin DD. Should COPD stand for “Comorbidities-related Obstructive Pulmonary Disease”? European Respiratory Journal 2015;46:901-2.
Molecular mechanisms underlying variations in lung function: a systems genetics analysis
Obeidat M, Hao K, Bossé Y, Nickle DC, Nie Y, Postma DS, Laviolette M, Sandford AJ, Daley DD, Hogg JC, Elliott WM, Fishbane N, Timens W, Hysi PG, Kaprio J, Wilson JF, Hui J, Rawal R, Schulz H, Stubbe B, Hayward C, Polasek O, Järvelin MR, Zhao JH, Jarvis D, Kähönen M, Franceschini N, North KE, Loth DW, Brusselle GG, Smith AV, Gudnason V, Bartz TM, Wilk JB, O'Connor GT, Cassano PA, Tang W, Wain LV, Artigas MS, Gharib SA, Strachan DP, Sin DD, Tobin MD, London SJ, Hall IP, Paré PD. Molecular mechanisms underlying variations in lung function: a systems genetics analysis. Lancet Respiratory Medicine 2015;3:782-95
The relationship between helicobacteri pylori seropositivity and chronic obstructive pulmonary
Sze MA, Chen YR, Tam S, Tashkin D, Wise RA, Connett JE, Man SFP, Sin DD. The relationship between helicobacteri pylori seropositivity and chronic obstructive pulmonary disease. Thorax 2015;70:923-9.
Oscillatory Positive Expiratory Pressure in Chronic Obstructive Pulmonary Disease
S Svenningsen, GA Paulin, K Sheikh, F Guo, A Hasany, M Kirby, R Etemad-Rezai, DG McCormack and G Parraga. Oscillatory Positive Expiratory Pressure in Chronic Obstructive Pulmonary Disease. Journal of Chronic Obstructive Lung Disease: COPD, 2015 Oct 2:1-9 DOI: 10.3109/15412555.2015.1043523
Non-Invasive Quantification of Alveolar Morphology in elderly never- and ex-smokers
GA Paulin, A Ouriadov, E Lessard, K Sheikh, DG McCormack and G Parraga. Non-Invasive Quantification of Alveolar Morphology in elderly never- and ex-smokers. Physiol Rep, 3 (9), 2015, e12583,doi: 10.14814/phy2.12583.
Characteristics of COPD in never-smokers and ever smokers in the general population: results from the CanCOLD study
Tan WC, Sin DD, Bourbeau J, Hernandez P, Chapman KR, Cowie R, FitzGerald JM, Marciniuk D, Maltais F, Buist AS, Road J, Hogg JC, Kirby M, Coxson H, Hague C, Leipsic J, O’Donnell DE, Aaron SD, CanCOLD Collaborative Research Group. Characteristics of COPD in never-smokers and ever smokers in the general population: results from the CanCOLD study. Thorax 2015;70:822-9
This is What COPD Looks Like
K Sheikh, HO Coxson and G Parraga. This is What COPD Looks Like. Respirology (2015) August 26 2015 doi: 10.1111/resp.12611 Epub ahead of print.
Ventilation Heterogeneity in Ex-smokers without Airflow Limitation
D Pike, M Kirby, F Guo, DG McCormack and G Parraga. Ventilation Heterogeneity in Ex-smokers without Airflow Limitation Acad Radiol. 2015 Aug;22(8):1068-78. doi: 10.1016/j.acra.2015.04.006. Epub 2015 May 23.2015.
Pulmonary CT and MRI that help explain COPD Pathophysiology and Outcomes
E.A. Hoffman, D.A. Lynch, R.G. Barr, E.J.R. van Beek, and G. Parraga. Pulmonary CT and MRI that help explain COPD Pathophysiology and Outcomes. J Magn Reson Imaging. 2015 Jul 22. doi: 10.1002/jmri.25010. [Epub ahead of print].
COPD: Do Imaging Measurements of Emphysema and Airway Disease Explain Symptoms and Exercise Capacity?
M Kirby, D Pike, DD Sin, HO Coxson, DG McCormack, and G Parraga. COPD: Do Imaging Measurements of Emphysema and Airway Disease Explain Symptoms and Exercise Capacity? Radiology. 2015 Jul 7:150037. [Epub ahead of print].
Serum bilirubin and disease progression in mild chronic obstructive pulmonary disease
Apperley S, Park HY, Holmes DT, Man SFP, Tashkin D, Wise RA, Connett JE, Sin DD. Serum bilirubin and disease progression in mild chronic obstructive pulmonary disease. Chest 2015;148:169-75
10-Year Trends in Direct Costs of COPD: A Population Based Study
Khakban A, Sin DD, FitzGerald JM, Ng R, Zafari Z, McManus B, Hollander Z, Marra CA, Sadatsafavi M. 10-Year Trends in Direct Costs of COPD: A Population Based Study. Chest. 2015 Sep 1;148(3):640-6. doi: 10.1378/chest.15-0721.
Globally Optimal co-Segmentation of Three-dimensional Pulmonary 1H and hyperpolarized 3He MRI with spatial consistence prior
F Guo, J Yuan, M Rajchl, S Svenningsen, DPI Capaldi, K Sheikh, A Fenster and G Parraga. Globally Optimal co-Segmentation of Three-dimensional Pulmonary 1H and hyperpolarized 3He MRI with spatial consistence prior. Med Image Anal 2015 Jul;23(1):43-55. doi: 10.1016/j.media.2015.04.001. Epub 2015 Apr 17.
Differences Hyperpolarized 3He Ventilation Imaging after 4 years in adults with Cystic Fibrosis
G Paulin, S Svenningsen, BN Jobse,S. Mohan, M Kirby, JF Lewis, and G Parraga. Differences Hyperpolarized 3He Ventilation Imaging after 4 years in adults with Cystic Fibrosis J Magn Reson Imaging. 2015 Jun;41(6):1701-7. doi: 10.1002/jmri.24744. Epub 2014 Aug 30.
Ultra-short echo-time pulmonary MRI: Evaluation and reproducibility in COPD subjects with and without bronchiectasis
W Ma, K Sheikh, S Svenningsen, D Pike, F Guo*, R Etemad-Rezai, J Leipsic, HO Coxson, DG McCormack and G Parraga. Ultra-short echo-time pulmonary MRI: Evaluation and reproducibility in COPD subjects with and without bronchiectasis. 2015 May;41(5):1465-74. doi: 10.1002/jmri.24680. Epub 2014 Jun 26.
Absolute leukocyte telomere length in HIV-infected and uninfected individuals: evidence of accelerated cell senescence in HIV-associated chronic obstructive pulmonary disease
Liu JC, Leung JM, Ngan DA, Nashta NF, Guillemi S, Harris M, Lima VD, Um SJ, Li Y, Tam S, Shaipanich T, Raju R, Hague C, Leipsic JA, Bourbeau J, Tan WC, Harrigan PR, Sin DD, Montaner J, Man SFP. Absolute leukocyte telomere length in HIV-infected and uninfected individuals: evidence of accelerated cell senescence in HIV-associated chronic obstructive pulmonary disease. Plos One 2015;10:e0124426.
Free-breathing Pulmonary and 3He MRI: Comparison in COPD and Bronchiectasis
DPI Capaldi, K Sheikh, F Guo, S Svenningsen, R Etemad-Rezai, HO Coxson, JA Leipsic, DG McCormack and G Parraga. Free-breathing Pulmonary and 3He MRI: Comparison in COPD and Bronchiectasis Acad Radiol. 2015 Mar;22(3):320-9. doi: 10.1016/j.acra.2014.10.003. Epub 2014 Dec 6
Pulmonary Imaging Abnormalities in an Adult Case of Congenital Lobar Emphysema
D Pike, S Mohan, W Ma, JF Lewis and G Parraga. Pulmonary Imaging Abnormalities in an Adult Case of Congenital Lobar Emphysema J Radiol Case Rep. 2015.Feb 28;9(2):9-15. 10.3941/jrcr.v912.2048. eCollection.
Pulmonary Artery Abnormalities in Ex-smokers with and without Airflow Limitation
TJ Lindenmaier, M Kirby, GA Paulin, L Mielniczuk, IA Cunningham, M Mura, C Licskai, and G Parraga. Pulmonary Artery Abnormalities in Ex-smokers with and without Airflow Limitation. J COPD. COPD, 0 : 1 – 11 , 2015. 1541-2555 print / 1541-2563 online DOI: 10.3109/15412555.2015.1074666.
Clinical relevance of fixed ratio vs lower limit of normal of FEV1/FVC in COPD: Patient-reported outcomes from the CanCOLD cohort
van Dijk WD, Tan W, Li PZ, Guo B, Li, S, Benedetti A, Bourbeau J, CanCOLD Study Group. Clinical relevance of fixed ratio vs lower limit of normal of FEV1/FVC in COPD: Patient-reported outcomes from the CanCOLD cohort. Annals of family medicine. 2015 Jan/Feb; 13 (1): 41-48
Pulmonary Functional Magnetic Resonance Imaging: Asthma Temporal-spatial Maps
S. Svenningsen, F Guo, M. Kirby, S. Choy, A Wheatley, DG. McCormack and G. Parraga. Pulmonary Functional Magnetic Resonance Imaging: Asthma Temporal-spatial Maps Acad Radiol. 2014 Nov;21(11):1402-10. doi: 10.1016/j.acra.2014.08.002.
Exacerbations in non-COPD patients: truth or myth-authors' response
Tan WC, Bourbeau J, Aaron S, FitzGerald JM, Hernandez P, Cowie R, Chapman KR, Marciniuk D, Maltais F, Buist S, O'Donnell D, Sin DD; CanCOLD Collaborative Research Group. Exacerbations in non-COPD patients: truth or myth-authors' response. Thorax. 2014 Nov; 69(11).
The COPD assessment test: a systematic review
Gupta N, Pinto LM, Morogan A, Bourbeau J. The COPD assessment test: a systematic review. Eur Respir J. 2014 Oct;44(4):873-84
What are ventilation defects in healthy elderly never-smokers?
K Sheikh, G Paulin, D Pike, S Svenningsen, NAM Paterson DG McCormack and G Parraga. What are ventilation defects in healthy elderly never-smokers? J Appl Physiol (1985). 2014 Aug 1;117(3):297-306. doi: 10.1152/japplphysiol.00046.2014. Epub 2014 Jun 5.
Exacerbation-like respiratory symptoms in individuals without chronic obstructive pulmonary disease: results from a population-based study
Tan WC, Bourbeau J, Hernandez P, Chapman KR, Cowie R, FitzGerald JM, Marciniuk DD, Maltais F, Buist AS, O'Donnell DE, Sin DD, Aaron SD, CanCOLD Collaborative Research Group. Exacerbation-like respiratory symptoms in individuals without chronic obstructive pulmonary disease: results from a population-based study. Thorax. 2014 Aug;69(8):709-17.
Hyperpolarized 3He and 129Xe MRI ADC: Physiological relevance in older never- and ex-smokers
M. Kirby, A Ouriadov, S Svenningsen, A Owrangi*, A Wheatley, R Etemad-Rezai, GE Santyr, DG McCormack and G Parraga. Hyperpolarized 3He and 129Xe MRI ADC: Physiological relevance in older never- and ex-smokers. Physiol Rep. 2014 Jul 16;2(7). pii: e12068. doi: 10.14814/phy2.12068.
Using Pulmonary Imaging to Move COPD Beyond FEV1
HO Coxson, J Leipsic, G Parraga and DD Sin. Using Pulmonary Imaging to Move COPD Beyond FEV1. Am J Resp Crit Care Med. 2014 Jul 15;190(2):135-44. doi: 10.1164/rccm.201402-0256PP. Review.
Economic and health effect of full adherence to controller therapy in adults with uncontrolled asthma: A simulation study
Zafari Z, Lynd LD, FitzGerald JM, Sadatsafavi M. Economic and health effect of full adherence to controller therapy in adults with uncontrolled asthma: A simulation study. J Allergy Clin Immunol. 2014 May 26.
Diagnosis, management, and prognosis of preschool wheeze
Ducharme FM, Tse SM, Chauhan B. Diagnosis, management, and prognosis of preschool wheeze. Lancet. 2014 May 3;383(9928):1593-604. doi: 10.1016/S0140-6736(14)60615-2.
Chapitres de livre
The Role of Magnetic Resonance Imaging in the Evaluation of Respiratory Disease
M. Kirby, HO Coxson and G Parraga. The Role of Magnetic Resonance Imaging in the Evaluation of Respiratory Disease. In Diagnostic Evaluation of the Respiratory System. Jaypee Brothers Medical Publishers JP Medical Ltd London SW1H 0HW UK info@jpmedpub.com www.jpmedpub.com 2015 Editor Claudio Sorino.